Refrigerated medicines stability tool
Search for advice on whether refrigerated medicines can or can't be used after exposure to out-of-range temperatures.
Information from both product licences and other sources is being shown Information from product licences only is being shown
Information in this tool is for use by registered healthcare professionals to inform their assessment of the impact of a temperature excursion on a medicine. Our article on Managing temperature excursions will also help users in determining their own local processes and risk assessment procedures in this area.
When medicines have been exposed to conditions outside their product licence, their subsequent use can still be appropriate but is off-label. We include information that is both within and outside the product licence. You can choose to just view only information from the product licence or include our extended data too.
When extended stability data is not available on the fridge tool, we recommend contacting the product's manufacturer directly. They may provide off-label temperature stability data and guidance on whether the product can be stored outside the refrigerator. Additionally, they can advise on any necessary adjustments to the product's expiry date to determine its suitability for continued use.
Adalimumab
Humira 40mg/0.4ml solution for injection pre-filled pens (AbbVie Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Humira 40mg/0.4ml solution for injection pre-filled syringes (AbbVie Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Humira 20mg/0.2ml solution for injection pre-filled syringes (AbbVie Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Amgevita 40mg/0.8ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Amgevita 40mg/0.8ml solution for injection pre-filled pens (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Hyrimoz 40mg/0.8ml solution for injection pre-filled pens (Sandoz Ltd)
Information as per product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Hyrimoz 40mg/0.8ml solution for injection pre-filled syringes (Sandoz Ltd)
Information as per product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Humira 80mg/0.8ml solution for injection pre-filled pens (AbbVie Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Amgevita 20mg/0.4ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Imraldi 40mg/0.8ml solution for injection pre-filled pens (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Imraldi 40mg/0.8ml solution for injection pre-filled syringes (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Aflibercept
Eylea 4mg/100microlitres solution for injection vials (Bayer Plc)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Eylea 3.6mg/90microlitres solution for injection pre-filled syringes (Bayer Plc)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Alirocumab
Praluent 75mg/1ml solution for injection pre-filled pens (Sanofi)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Praluent 150mg/1ml solution for injection pre-filled pens (Sanofi)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Praluent 300mg/2ml solution for injection pre-filled pens (Sanofi)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Alprostadil
Muse 500microgram urethral sticks (Viatris UK Healthcare Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Muse 1000microgram urethral sticks (Viatris UK Healthcare Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Vitaros 3mg/g cream (The Simple Pharma Company UK Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Amikacin liposomal
Arikayce liposomal 590mg nebuliser dispersion vials with Lamira Nebuliser Handset (Insmed Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Anakinra
Kineret 100mg/0.67ml solution for injection pre-filled syringes (Swedish Orphan Biovitrum Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Angiotensin II
Giapreza 2.5mg/1ml concentrate for solution for infusion vials (PAION Netherlands B.V.)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 6 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Anidulafungin
Ecalta 100mg powder for concentrate for solution for infusion vials (Pfizer Ltd)
Information outside product licence
| Maximum Time For excursion | 15 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
Manufacturer provided to SPS
Anti-D immunoglobulin
D-Gam Anti-D immunoglobulin 500unit solution for injection vials (Bio Products Laboratory Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 8 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Antithymocyte immunoglobulin (rabbit)
Thymoglobuline 25mg powder and solvent for solution for infusion vials (Sanofi)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Argipressin
Argipressin 20units/1ml solution for injection ampoules (AOP Orphan Ltd)
Information outside product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Asfotase alfa
Strensiq 40mg/1ml solution for injection vials (Alexion Pharma UK Ltd)
Information as per product licence
| Maximum Time For excursion | 3 hours |
|---|---|
| Temperature Range For excursion | 8°C to 27 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Strensiq 80mg/0.8ml solution for injection vials (Alexion Pharma UK Ltd)
Information as per product licence
| Maximum Time For excursion | 3 hours |
|---|---|
| Temperature Range For excursion | 8°C to 27 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Atracurium
Atracurium besilate 50mg/5ml solution for injection ampoules (Pfizer Ltd)
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Atracurium besilate 25mg/2.5ml solution for injection ampoules (Pfizer Ltd)
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Atracurium besilate 250mg/25ml solution for injection vials (Pfizer Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Atracurium besilate 25mg/2.5ml solution for injection ampoules (Hikma Pharmaceuticals International Ltd)
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised by SPS Quality Assurance.
Atracurium besilate 50mg/5ml solution for injection ampoules (Hikma Pharmaceuticals International Ltd)
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised by SPS QA.
Atracurium besilate 25mg/2.5ml solution for injection ampoules (AS Kalceks)
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Atracurium besilate 50mg/5ml solution for injection ampoules (AS Kalceks)
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Aztreonam
Cayston 75mg powder and solvent for nebuliser solution vials with Altera Nebuliser Handset (Gilead Sciences Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 672 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Beclometasone + Formoterol
Fostair 100micrograms/dose / 6micrograms/dose inhaler (Chiesi Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Fostair 200micrograms/dose / 6micrograms/dose inhaler (Chiesi Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Luforbec 100micrograms/dose / 6micrograms/dose inhaler (Lupin Healthcare (UK) Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Luforbec 200micrograms/dose / 6micrograms/dose inhaler (Lupin Healthcare (UK) Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Beclometasone + Formoterol + Glycopyrronium bromide
Trimbow 87micrograms/dose / 5micrograms/dose / 9micrograms/dose inhaler (Chiesi Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 56 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
This information applies only to the 60 actuation pressurised container.
Excursion Case
Information as per product licence
| Maximum Time For excursion | 112 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
This information applies only to the 120 actuation pressurised container.
Trimbow 172micrograms/dose / 5micrograms/dose / 9micrograms/dose inhaler (Chiesi Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 56 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
This information applies only to the 60 actuation pressurised container.
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
This information applies only to the 120 actuation pressurised container.
Belimumab
Benlysta 400mg powder for concentrate for solution for infusion vials (GlaxoSmithKline UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Protect from light. If product exposed to light, maximum time for excursion is reduced to 72 hours.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | -25 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Benlysta 120mg powder for concentrate for solution for infusion vials (GlaxoSmithKline UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Protect from light. If product exposed to light, maximum time for excursion is reduced to 72 hours.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | -25 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Benlysta 200mg/1ml solution for injection pre-filled pens (GlaxoSmithKline UK Ltd)
Information as per product licence
| Maximum Time For excursion | 12 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Benralizumab
Fasenra 30mg/1ml solution for injection pre-filled pens (AstraZeneca UK Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Benzoyl peroxide + Clindamycin
Duac Once Daily gel (3% and 1%) (Stiefel Laboratories (UK) Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 40°C, the maximum time for excursion is reduced to 4 hours.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 6 Days |
|---|---|
| Temperature Range For excursion | -1 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Duac Once Daily gel (5% and 1%) (Stiefel Laboratories (UK) Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 40°C, the maximum time for excursion is reduced to 4 hours.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 6 Days |
|---|---|
| Temperature Range For excursion | -1 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Beractant
Survanta 200mg/8ml endotracheopulmonary suspension bottles (AbbVie Ltd)
Information outside product licence
| Maximum Time For excursion | 8 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Bevacizumab
Vegzelma 400mg/16ml concentrate for solution for infusion vials (Celltrion Healthcare UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 12 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Product can be used up until 36 months or original expiry date if this comes first
Source for off-label information
Manufacturer off-label data
Excursion Case
Information outside product licence
| Maximum Time For excursion | 12 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Product can be used up until 36 months or original expiry date if this comes first
Source for off-label information
Manufacturer off-label data
Bimekizumab
Bimzelx 160mg/1ml solution for injection pre-filled syringes (UCB Pharma Ltd)
Information as per product licence
| Maximum Time For excursion | 25 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Bimzelx 160mg/1ml solution for injection pre-filled pens (UCB Pharma Ltd)
Information as per product licence
| Maximum Time For excursion | 25 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Brodalumab
Kyntheum 210mg/1.5ml solution for injection pre-filled syringes (LEO Pharma)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Brolucizumab
Beovu 19.8mg/0.165ml solution for injection pre-filled syringes (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Bulevirtide
Hepcludex 2mg powder for solution for injection vials (Gilead Sciences Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 56 Days |
|---|---|
| Temperature Range For excursion | -40 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Burosumab
Crysvita 10mg/1ml solution for injection vials (Kyowa Kirin Ltd)
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Crysvita 20mg/1ml solution for injection vials (Kyowa Kirin Ltd)
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Crysvita 30mg/1ml solution for injection vials (Kyowa Kirin Ltd)
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Caplacizumab
Cablivi 10mg powder and solvent for solution for injection vials (Sanofi Genzyme)
Information as per product licence
| Maximum Time For excursion | 56 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Carboprost
Hemabate 250micrograms/1ml solution for injection ampoules (Pfizer Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 15 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Source for off-label information
Manufacturer's website.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Carglumic acid
Carbaglu 200mg dispersible tablets (Recordati Rare Diseases UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 9 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 9 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Cefiderocol
Fetcroja 1g powder for concentrate for solution for infusion vials (Shionogi BV)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Certolizumab pegol
Cimzia 200mg/1ml solution for injection pre-filled syringes (UCB Pharma Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 10 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Discard product if exposed to greater than one excursion.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 10 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Discard product if exposed to greater than one excursion.
Source for off-label information
As advised to SPS by manufacturer.
Cimzia 200mg/1ml solution for injection pre-filled pens (UCB Pharma Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 10 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Discard product if exposed to greater than one excursion.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 10 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Discard product if exposed to greater than one excursion.
Source for off-label information
As advised to SPS by manufacturer.
Cimzia 200mg/1ml solution for injection in a dose-dispenser cartridge (UCB Pharma Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 10 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Discard product if exposed to greater than one excursion.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 10 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Discard product if exposed to greater than one excursion.
Source for off-label information
As advised to SPS by manufacturer.
Chloramphenicol
Minims chloramphenicol 0.5% eye drops 0.5ml unit dose (Bausch & Lomb UK Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Chlormethine
Ledaga 160micrograms/g gel (Recordati Rare Diseases UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 12 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -15 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Cholera vaccine
Dukoral cholera vaccine effervescent powder and suspension for oral suspension (Valneva UK Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Choriogonadotropin alfa
Ovitrelle 250micrograms/0.5ml solution for injection pre-filled syringes (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Cladribine
Litak 10mg/5ml solution for injection vials (Lipomed GmbH)
Information outside product licence
| Maximum Time For excursion | 730 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 30°C, the maximum time for excursion is reduced to 1 year.
Source for off-label information
As advised to SPS by manufacturer.
Crisantaspase
Erwinase 10,000unit powder for solution for injection vials (Porton Biopharma Ltd)
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Daratumumab
Darzalex 1800mg/15ml solution for injection vials (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Darbepoetin alfa
Aranesp 20micrograms/0.5ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp 30micrograms/0.3ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp 40micrograms/0.4ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp 50micrograms/0.5ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp 60micrograms/0.3ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp 10micrograms/0.4ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp 80micrograms/0.4ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp 100micrograms/0.5ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp 150micrograms/0.3ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp 500micrograms/1ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp 300micrograms/0.6ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp SureClick 500micrograms/1ml solution for injection pre-filled pens (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp SureClick 20micrograms/0.5ml solution for injection pre-filled pens (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp SureClick 40micrograms/0.4ml solution for injection pre-filled pens (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp SureClick 60micrograms/0.3ml solution for injection pre-filled pens (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp SureClick 80micrograms/0.4ml solution for injection pre-filled pens (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp SureClick 100micrograms/0.5ml solution for injection pre-filled pens (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp SureClick 150micrograms/0.3ml solution for injection pre-filled pens (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp SureClick 300micrograms/0.6ml solution for injection pre-filled pens (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aranesp 130micrograms/0.65ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Denosumab
Prolia 60mg/1ml solution for injection pre-filled syringes (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Xgeva 120mg/1.7ml solution for injection vials (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Digoxin specific antibody
DigiFab 40mg powder for solution for infusion vials (Protherics Medicines Development Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Diphtheria + Tetanus + Pertussis + Hepatitis B + Poliomyelitis + Haemophilus influenzae type B vaccine
Infanrix Hexa vaccine powder and suspension for suspension for injection 0.5ml pre-filled syringes (GlaxoSmithKline UK Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Vaxelis vaccine suspension for injection 0.5ml pre-filled syringes (Sanofi)
Information as per product licence
| Maximum Time For excursion | 9 Days 12 Hrs |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Diphtheria + Tetanus + Pertussis + Poliomyelitis vaccine
Boostrix-IPV suspension for injection 0.5ml pre-filled syringes (GlaxoSmithKline UK Ltd)
Information as per product licence
| Maximum Time For excursion | 8 hours |
|---|---|
| Temperature Range For excursion | 8°C to 21 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Dornase alfa
Pulmozyme 2.5mg nebuliser liquid 2.5ml ampoules (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Dostarlimab
Jemperli 500mg/10ml concentrate for solution for infusion vials (GlaxoSmithKline UK Ltd)
Information outside product licence
| Maximum Time For excursion | 40 hours |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Doxorubicin
Doxorubicin 50mg/25ml solution for infusion vials (medac UK)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 12 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If excursion time exceeds 12 hours, use product within 14 days.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | Use product expiry date |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Doxorubicin 200mg/100ml solution for infusion vials (medac UK)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 12 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If excursion time exceeds 12 hours, use product within 14 days.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | Use product expiry date |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Doxorubicin 10mg/5ml solution for infusion vials (medac UK)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 12 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If excursion time exceeds 12 hours, use product within 14 days.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | Use product expiry date |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Doxycycline
Doxycyclin-ratiopharm SF 100mg/5ml solution for injection ampoules (Imported (Germany))
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Dulaglutide
Trulicity 0.75mg/0.5ml solution for injection pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Trulicity 1.5mg/0.5ml solution for injection pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Trulicity 3mg/0.5ml solution for injection pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Trulicity 4.5mg/0.5ml solution for injection pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Dupilumab
Dupixent 300mg/2ml solution for injection pre-filled syringes (Sanofi Genzyme)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
We recommend contacting the product's manufacturer directly. They may provide off-label temperature stability data and guidance on whether the product can be stored back into the refrigerator. Additionally, they can advise on any necessary adjustments to the product's expiry date to determine its suitability for continued use.
Dupixent 200mg/1.14ml solution for injection pre-filled syringes (Sanofi Genzyme)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
We recommend contacting the product's manufacturer directly. They may provide off-label temperature stability data and guidance on whether the product can be stored back into the refrigerator. Additionally, they can advise on any necessary adjustments to the product's expiry date to determine its suitability for continued use.
Dupixent 200mg/1.14ml solution for injection pre-filled pens (Sanofi Genzyme)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
We recommend contacting the product's manufacturer directly. They may provide off-label temperature stability data and guidance on whether the product can be stored back into the refrigerator. Additionally, they can advise on any necessary adjustments to the product's expiry date to determine its suitability for continued use.
Dupixent 300mg/2ml solution for injection pre-filled pens (Sanofi Genzyme)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
We recommend contacting the product's manufacturer directly. They may provide off-label temperature stability data and guidance on whether the product can be stored back into the refrigerator. Additionally, they can advise on any necessary adjustments to the product's expiry date to determine its suitability for continued use.
Eculizumab
Soliris 300mg/30ml concentrate for solution for infusion vials (Alexion Pharma UK Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Efgartigimod alfa
Vyvgart 1000mg/5.6ml solution for injection vials (Argenx UK Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Emicizumab
Hemlibra 30mg/1ml solution for injection vials (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Hemlibra 60mg/0.4ml solution for injection vials (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Hemlibra 105mg/0.7ml solution for injection vials (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Hemlibra 150mg/1ml solution for injection vials (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Enfortumab vedotin
Padcev 30mg powder for concentrate for solution for infusion vials (Astellas Pharma Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 40 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | -80 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Epoetin alfa
Eprex 4,000units/0.4ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Eprex 2,000units/0.5ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Eprex 3,000units/0.3ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Eprex 5,000units/0.5ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Eprex 6,000units/0.6ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Eprex 8,000units/0.8ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Eprex 10,000units/1ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Eprex 20,000units/0.5ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Eprex 40,000units/1ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Eprex 30,000units/0.75ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Epoetin beta
NeoRecormon 500units/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
NeoRecormon 2,000units/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
NeoRecormon 3,000units/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
NeoRecormon 4,000units/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
NeoRecormon 5,000units/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
NeoRecormon 6,000units/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
NeoRecormon 10,000units/0.6ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
NeoRecormon 20,000units/0.6ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
NeoRecormon 30,000units/0.6ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Epoetin zeta
Retacrit 1,000units/0.3ml solution for injection pre-filled syringes (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Retacrit 2,000units/0.6ml solution for injection pre-filled syringes (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Retacrit 3,000units/0.9ml solution for injection pre-filled syringes (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Retacrit 4,000units/0.4ml solution for injection pre-filled syringes (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Retacrit 5,000units/0.5ml solution for injection pre-filled syringes (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Retacrit 6,000units/0.6ml solution for injection pre-filled syringes (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Retacrit 8,000units/0.8ml solution for injection pre-filled syringes (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Retacrit 10,000units/1ml solution for injection pre-filled syringes (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Retacrit 40,000units/1ml solution for injection pre-filled syringes (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Retacrit 20,000units/0.5ml solution for injection pre-filled syringes (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Retacrit 30,000units/0.75ml solution for injection pre-filled syringes (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Eptifibatide
Eptifibatide 75mg/100ml solution for infusion vials (Kensington Pharma Ltd)
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised by the manufacturer to SPS
Eptifibatide 20mg/10ml solution for injection vials (Kensington Pharma Ltd)
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised by the manufacturer to SPS
Eravacycline
Xerava 100mg powder for concentrate for solution for infusion vials (PAION Netherlands B.V.)
Information outside product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Erenumab
Aimovig 70mg/1ml solution for injection pre-filled pens (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Aimovig 140mg/1ml solution for injection pre-filled pens (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Ergometrine
Ergometrine 500micrograms/1ml solution for injection ampoules (hameln pharma Ltd)
Information outside product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Ergometrine + Oxytocin
Syntometrine 500micrograms/1ml solution for injection ampoules (Alliance Pharmaceuticals Ltd)
Information as per product licence
| Maximum Time For excursion | 56 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Etanercept
Benepali 50mg/1ml solution for injection pre-filled syringes (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 31 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Benepali 50mg/1ml solution for injection pre-filled pens (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 31 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Benepali 25mg/0.5ml solution for injection pre-filled syringes (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 31 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Ethinylestradiol + Etonogestrel
NuvaRing 0.12mg/0.015mg per day vaginal delivery system (Organon Pharma (UK) Ltd)
Information as per product licence
| Maximum Time For excursion | 112 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
European viper snake venom antiserum
ViperaTAb 100mg/4ml concentrate for solution for infusion vials (Special Order)
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Evolocumab
Repatha SureClick 140mg/1ml solution for injection pre-filled pens (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Exenatide
Bydureon BCise 2mg/0.85ml prolonged-release suspension for injection pre-filled pens (AstraZeneca UK Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Factor VIII + von Willebrand factor
Dried Factor VIII Fraction type 8Y 250unit powder and solvent for solution for injection vials (Bio Products Laboratory Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
Provided to SPS by the manufacturer
Dried Factor VIII Fraction type 8Y 500unit powder and solvent for solution for injection vials (Bio Products Laboratory Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
Provided to SPS by the manufacturer
Faricimab
Vabysmo 28.8mg/0.24ml solution for injection vials (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Filgrastim
Nivestim 12million units/0.2ml solution for injection pre-filled syringes (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 15 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Excursion Case
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If exposure longer than 24 hours or product defrosted and re-frozen, then discard.
Nivestim 30million units/0.5ml solution for injection pre-filled syringes (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 15 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Excursion Case
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If exposure longer than 24 hours or product defrosted and re-frozen, then discard.
Nivestim 48million units/0.5ml solution for injection pre-filled syringes (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 15 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Stability Data and Comments
Please also refer to the manufacturer’s product literature for recommended storage information.
Excursion Case
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If exposure longer than 24 hours or product defrosted and re-frozen, then discard.
Zarzio 30million units/0.5ml solution for injection pre-filled syringes (Sandoz Ltd)
Information as per product licence
| Maximum Time For excursion | 8 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Zarzio 48million units/0.5ml solution for injection pre-filled syringes (Sandoz Ltd)
Information as per product licence
| Maximum Time For excursion | 8 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Fludrocortisone
Fludrocortisone 100microgram tablets (Aspen Pharma Trading Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Folinic acid
Calcium folinate 15mg/2ml solution for injection ampoules (Pfizer Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Calcium folinate 300mg/30ml solution for injection vials (Pfizer Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Calcium folinate 100mg/10ml solution for injection vials (Pfizer Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Calcium folinate 50mg/5ml solution for injection vials (Pfizer Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufactuer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Follitropin alfa
Gonal-f 300units/0.5ml solution for injection pre-filled pens (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Stability Data and Comments
If the unopened pack has been removed from the refrigerator and reached a temperature above 8°C, then it can either be stored at room temperature (≤25°C) or put back in the refrigerator (2°C-8°C).
Gonal-f 450units/0.75ml solution for injection pre-filled pens (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Stability Data and Comments
If the unopened pack has been removed from the refrigerator and reached a temperature above 8°C, then it can either be stored at room temperature (≤25°C) or put back in the refrigerator (2°C-8°C).
Gonal-f 900units/1.5ml solution for injection pre-filled pens (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Stability Data and Comments
If the unopened pack has been removed from the refrigerator and reached a temperature above 8°C, then it can either be stored at room temperature (≤25°C) or put back in the refrigerator (2°C-8°C).
Ovaleap 900units/1.5ml solution for injection cartridges (Theramex HQ UK Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Follitropin delta
Rekovelle 12micrograms/0.36ml solution for injection pre-filled pens (Ferring Pharmaceuticals Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Rekovelle 72micrograms/2.16 ml solution for injection pre-filled pens (Ferring Pharmaceuticals Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Rekovelle 36micrograms/1.08ml solution for injection pre-filled pens (Ferring Pharmaceuticals Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Formoterol
Atimos Modulite 12micrograms/dose inhaler (Chiesi Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Fosphenytoin
Pro-Epanutin 750mg/10ml concentrate for solution for injection vials (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Fremanezumab
Ajovy 225mg/1.5ml solution for injection pre-filled pens (Teva UK Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Fulvestrant
Faslodex 250mg/5ml solution for injection pre-filled syringes (AstraZeneca UK Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Excursion Case
Information as per product licence
| Maximum Time For excursion | Use product expiry date |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Galcanezumab
Emgality 120mg/1ml solution for injection pre-filled pens (Organon Pharma (UK) Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Gemtuzumab ozogamicin
Mylotarg 5mg powder for concentrate for solution for infusion vials (Pfizer Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Glucagon
GlucaGen Hypokit 1mg powder and solvent for solution for injection (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 504 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Stability Data and Comments
Please note that 504 days equates to 18 months when calculated using a 28 day month.
Golimumab
Simponi 50mg/0.5ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Simponi 50mg/0.5ml solution for injection pre-filled pens (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Simponi 100mg/1ml solution for injection pre-filled pens (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Haem arginate
Normosang 250mg/10ml solution for infusion ampoules (Recordati Rare Diseases UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 9 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If the temperature exceeds 30°C but remains below 40°C, the maximum time for the excursion is 3 days.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 9 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Haemophilus influenzae type b + Meningococcal group C vaccine
Menitorix vaccine powder and solvent for solution for injection 0.5ml vials (GlaxoSmithKline UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 37 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | Use product expiry date |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Hepatitis A + B vaccine
Twinrix Adult vaccine suspension for injection 1ml pre-filled syringes (GlaxoSmithKline UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | Use product expiry date |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Twinrix Paediatric vaccine suspension for injection 0.5ml pre-filled syringes (GlaxoSmithKline UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | Use product expiry date |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Ambirix vaccine suspension for injection 1ml pre-filled syringes (GlaxoSmithKline UK Ltd)
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Hepatitis A vaccine
Havrix Junior Monodose vaccine suspension for injection 0.5ml pre-filled syringes (GlaxoSmithKline UK Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Havrix Monodose vaccine suspension for injection 1ml pre-filled syringes (GlaxoSmithKline UK Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Hepatitis B immunoglobulin
Hepatitis B immunoglobulin human 500units/5ml solution for injection vials (Bio Products Laboratory Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Protect from light. The manufacturer has stated that an additional 24 hours of storage at temperatures up to 25°C may be permitted if the conditions have not been exceeded. We recommend that the manufacturer is contacted so that they they can advise on any necessary adjustments to the product's storage and expiry date to determine its suitability for continued use.
Source for off-label information
Provided by manufacturer to SPS
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Hepatitis B vaccine
Engerix B 20micrograms/1ml vaccine suspension for injection pre-filled syringes (GlaxoSmithKline UK Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 37°C, the maximum time for excursion is reduced to 72 hours.
Engerix B 10micrograms/0.5ml vaccine suspension for injection pre-filled syringes (GlaxoSmithKline UK Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 37°C, the maximum time for excursion is reduced to 72 hours.
High Purity Factor IX
Replenine-VF 500unit powder and solvent for solution for injection vials (Bio Products Laboratory Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Replenine-VF 1,000unit powder and solvent for solution for injection vials (Bio Products Laboratory Ltd)
Information outside product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Protect from light. The manufacturer has stated that subsequently up to 1 week of additional storage at up to 25°C can be permitted. We advise that the manufacturer is contacted so that they can advise on any necessary adjustments to the product's expiry date to determine its suitability for continued use.
Source for off-label information
Provided by the manufacturer to SPS
Human papillomavirus vaccine
Gardasil 9 vaccine suspension for injection 0.5ml pre-filled syringes (Merck Sharp & Dohme (UK) Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 4 Days |
|---|---|
| Temperature Range For excursion | 8°C to 40 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Excursion Case
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Hydroxycarbamide
Xromi 100mg/ml oral solution (Nova Laboratories Ltd)
Information outside product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Idarucizumab
Praxbind 2.5g/50ml solution for infusion vials (Boehringer Ingelheim Ltd)
Information as per product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Protect from light. If product exposed to light, maximum time for excursion is reduced to 6 hours.
Idursulfase
Elaprase 6mg/3ml concentrate for solution for infusion vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 8 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Infliximab
Remicade 100mg powder for concentrate for solution for infusion vials (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Flixabi 100mg powder for concentrate for solution for infusion vials (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Remsima 120mg/1ml solution for injection pre-filled pens (Celltrion Healthcare UK Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 12 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
Reduce expiry date to 24 months or original expiry date if this is earlier
Source for off-label information
Manufacturer off-label data.
Influenza vaccine
Fluenz Tetra vaccine nasal suspension 0.2ml unit dose (AstraZeneca UK Ltd)
Information as per product licence
| Maximum Time For excursion | 12 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Inotuzumab ozogamicin
Besponsa 1mg powder for concentrate for solution for infusion vials (Pfizer Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 365 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Stability Data and Comments
This advice applies to a single temperature excursion.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Stability Data and Comments
This advice applies to a single temperature excursion.
Source for off-label information
As advised to SPS by manufacturer.
Insulin aspart
NovoRapid Penfill 100units/ml solution for injection 3ml cartridges (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
NovoRapid 100units/ml solution for injection 10ml vials (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
NovoRapid FlexPen 100units/ml solution for injection 3ml pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
NovoRapid FlexTouch 100units/ml solution for injection 3ml pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
NovoRapid PumpCart 100units/ml solution for injection 1.6ml cartridges (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Following the temperature excursion, the PumpCart can be used for up to 7 more days below 37°C in an insulin infusion pump system.
Fiasp FlexTouch 100units/ml solution for injection 3ml pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Fiasp Penfill 100units/ml solution for injection 3ml cartridges (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Fiasp 100units/ml solution for injection 10ml vials (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Insulin aspart biphasic
NovoMix 30 FlexPen 100units/ml suspension for injection 3ml pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
NovoMix 30 Penfill 100units/ml suspension for injection 3ml cartridges (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Insulin degludec + Liraglutide
Xultophy 100units/ml / 3.6mg/ml solution for injection 3ml pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Insulin detemir
Levemir FlexPen 100units/ml solution for injection 3ml pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 42 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Levemir Penfill 100units/ml solution for injection 3ml cartridges (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 42 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Insulin glargine
Lantus 100units/ml solution for injection 3ml cartridges (Sanofi)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Lantus 100units/ml solution for injection 10ml vials (Sanofi)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Lantus 100units/ml solution for injection 3ml pre-filled SoloStar pens (Sanofi)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Toujeo 300units/ml solution for injection 1.5ml pre-filled SoloStar pens (Sanofi)
Information as per product licence
| Maximum Time For excursion | 42 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Store away from direct heat or direct light. Pens in use must not be stored in the refrigerator.
Abasaglar KwikPen 100units/ml solution for injection 3ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Abasaglar 100units/ml solution for injection 3ml cartridges (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Toujeo 300units/ml solution for injection 3ml pre-filled DoubleStar pens (Sanofi)
Information as per product licence
| Maximum Time For excursion | 42 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Store away from direct heat or direct light. Pens in use must not be stored in the refrigerator.
Abasaglar Tempo Pen 100units/ml solution for injection 3ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Insulin glulisine
Apidra 100units/ml solution for injection 3ml cartridges (Sanofi)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Pens or cartridge in use must not be stored in the refrigerator.
Apidra 100units/ml solution for injection 10ml vials (Sanofi)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Apidra 100units/ml solution for injection 3ml pre-filled SoloStar pens (Sanofi)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Pens or cartridge in use must not be stored in the refrigerator.
Insulin isophane biphasic human
Insuman Comb 25 100units/ml suspension for injection 3ml cartridges (Sanofi)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Humulin M3 100units/ml suspension for injection 3ml cartridges (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Humulin M3 100units/ml suspension for injection 10ml vials (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Humulin M3 KwikPen 100units/ml suspension for injection 3ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Insuman Comb 25 100units/ml suspension for injection 3ml pre-filled SoloStar pens (Sanofi)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Insulin isophane biphasic porcine
Hypurin Porcine 30/70 Mix 100units/ml suspension for injection 10ml vials (C P Pharmaceuticals Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 35°C, the maximum time for excursion is reduced to 5 weeks.
Source for off-label information
As advised to SPS by manufacturer.
Hypurin Porcine 30/70 Mix 100units/ml suspension for injection 3ml cartridges (C P Pharmaceuticals Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 35°C, the maximum time for excursion is reduced to 5 weeks.
Source for off-label information
As advised to SPS by manufacturer.
Insulin isophane human
Humulin I 100units/ml suspension for injection 10ml vials (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Humulin I 100units/ml suspension for injection 3ml cartridges (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Insuman Basal 100units/ml suspension for injection 3ml cartridges (Sanofi)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Humulin I KwikPen 100units/ml suspension for injection 3ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Insuman Basal 100units/ml suspension for injection 3ml pre-filled SoloStar pens (Sanofi)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Insulin isophane porcine
Hypurin Porcine Isophane 100units/ml suspension for injection 10ml vials (C P Pharmaceuticals Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 35°C, the maximum time for excursion is reduced to 5 weeks.
Source for off-label information
As advised to SPS by manufacturer.
Hypurin Porcine Isophane 100units/ml suspension for injection 3ml cartridges (C P Pharmaceuticals Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 35°C, the maximum time for excursion is reduced to 5 weeks.
Source for off-label information
As advised to SPS by manufacturer.
Insulin lispro
Humalog 100units/ml solution for injection 10ml vials (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Humalog 100units/ml solution for injection 3ml cartridges (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Humalog KwikPen 100units/ml solution for injection 3ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Humalog KwikPen 200units/ml solution for injection 3ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Insulin lispro biphasic
Humalog Mix50 100units/ml suspension for injection 3ml cartridges (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Humalog Mix25 KwikPen 100units/ml suspension for injection 3ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Humalog Mix50 KwikPen 100units/ml suspension for injection 3ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Humalog Mix25 100units/ml suspension for injection 10ml vials (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Insulin soluble human
Humulin S 100units/ml solution for injection 3ml cartridges (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Humulin S 100units/ml solution for injection 10ml vials (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Insulin soluble porcine
Hypurin Porcine Neutral 100units/ml solution for injection 10ml vials (C P Pharmaceuticals Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Hypurin Porcine Neutral 100units/ml solution for injection 3ml cartridges (C P Pharmaceuticals Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Interferon beta-1a
Rebif 44micrograms/0.5ml (12million units) solution for injection pre-filled syringes (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Rebif 22micrograms/0.5ml (6million units) solution for injection pre-filled syringes (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Rebif 8.8micrograms/0.2ml (2.4million units) solution for injection pre-filled syringes (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Rebif 22micrograms/0.5ml (6million units) solution for injection pre-filled syringes and Rebif 8.8micrograms/0.2ml (2.4million units) solution for injection pre-filled syringes (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Rebif 22micrograms/0.5ml (6million units) solution for injection 1.5ml cartridges (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Rebif 44micrograms/0.5ml (12million units) solution for injection 1.5ml cartridges (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Rebif 22micrograms/0.5ml (6million units) solution for injection pre-filled pens (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Rebif 44micrograms/0.5ml (12million units) solution for injection pre-filled pens (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Rebif 8.8micrograms/0.2ml (2.4million units) solution for injection pre-filled pens (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Rebif 22micrograms/0.5ml (6million units) solution for injection pre-filled pens and Rebif 8.8micrograms/0.2ml (2.4million units) solution for injection pre-filled pens (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Isavuconazole
Cresemba 200mg powder for concentrate for solution for infusion vials (Pfizer Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 3 Days 18 Hrs |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | -40 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Ixekizumab
Taltz 80mg/1ml solution for injection pre-filled syringes (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 5 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Taltz 80mg/1ml solution for injection pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 5 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Lanreotide
Somatuline Autogel 60mg/0.5ml solution for injection pre-filled syringes with safety system (Ipsen Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 40 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
This product can be returned to the fridge for later use as long as it has not been subjected to more than 3 temperature excursions, or has been exposed for more than 72 hours in total.
Somatuline Autogel 90mg/0.5ml solution for injection pre-filled syringes with safety system (Ipsen Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 40 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
This product can be returned to the fridge for later use as long as it has not been subjected to more than 3 temperature excursions, or has been exposed for more than 72 hours in total.
Somatuline Autogel 120mg/0.5ml solution for injection pre-filled syringes with safety system (Ipsen Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 40 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
This product can be returned to the fridge for later use as long as it has not been subjected to more than 3 temperature excursions, or has been exposed for more than 72 hours in total.
Latanoprost + Timolol
Xalacom eye drops (Viatris UK Healthcare Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Lidocaine + Hydrocortisone
Xyloproct 5%/0.275% ointment (Aspen Pharma Trading Ltd)
Information as per product licence
| Maximum Time For excursion | 56 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Lipegfilgrastim
Lonquex 6mg/0.6ml solution for injection pre-filled syringes (Teva UK Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Liraglutide
Victoza 6mg/ml solution for injection 3ml pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Saxenda 6mg/ml solution for injection 3ml pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Lixisenatide
Lyxumia 20micrograms/0.2ml solution for injection 3ml pre-filled pens (Sanofi)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Lopinavir + Ritonavir
Kaletra 80mg/20mg/1ml oral solution (AbbVie Ltd)
Information as per product licence
| Maximum Time For excursion | 42 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Lorazepam
Lorazepam 4mg/1ml solution for injection ampoules (Macure Pharma UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Stability Data and Comments
Product is also stable for up to three temperature excursions of not more than 24 hours each.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -17 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Meningococcal group B vaccine
Bexsero vaccine suspension for injection 0.5ml pre-filled syringes (GlaxoSmithKline UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | Use product expiry date |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Meningococcal groups A + C + W135 + Y vaccine
Menveo vaccine powder and solvent for solution for injection 0.5ml vials (GlaxoSmithKline UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 5 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | Use product expiry date |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Methoxy polyethylene glycol-epoetin beta
Mircera 50micrograms/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mircera 100micrograms/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mircera 150micrograms/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mircera 200micrograms/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mircera 75micrograms/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mircera 250micrograms/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mircera 30micrograms/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mircera 120micrograms/0.3ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mircera 360micrograms/0.6ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Moroctocog alfa
ReFacto AF 500unit powder and solvent for solution for injection vials (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -5 °C to 2°C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
ReFacto AF 1,000unit powder and solvent for solution for injection vials (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -5 °C to 2°C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
ReFacto AF 250unit powder and solvent for solution for injection vials (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -5 °C to 2°C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
ReFacto AF 2,000unit powder and solvent for solution for injection vials (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -5 °C to 2°C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
ReFacto AF 3,000unit powder and solvent for solution for injection pre-filled syringes (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -5 °C to 2°C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
ReFacto AF 2,000unit powder and solvent for solution for injection pre-filled syringes (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -5 °C to 2°C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
ReFacto AF 1,000unit powder and solvent for solution for injection pre-filled syringes (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -5 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
ReFacto AF 500unit powder and solvent for solution for injection pre-filled syringes (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -5 °C to 2°C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
ReFacto AF 250unit powder and solvent for solution for injection pre-filled syringes (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -5 °C to 2°C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within original expiry date | Yes |
Natalizumab
Tysabri 150mg/1ml solution for injection pre-filled syringes (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Nitisinone
Orfadin 2mg capsules (Swedish Orphan Biovitrum Ltd)
Information as per product licence
| Maximum Time For excursion | 56 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Orfadin 5mg capsules (Swedish Orphan Biovitrum Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Orfadin 10mg capsules (Swedish Orphan Biovitrum Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Orfadin 20mg capsules (Swedish Orphan Biovitrum Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Orfadin 4mg/1ml oral suspension (Swedish Orphan Biovitrum Ltd)
Information as per product licence
| Maximum Time For excursion | 56 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Nivolumab
Opdivo 100mg/10ml concentrate for solution for infusion vials (Bristol-Myers Squibb Pharmaceuticals Ltd)
Information as per product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Opdivo 240mg/24ml concentrate for solution for infusion vials (Bristol-Myers Squibb Pharmaceuticals Ltd)
Information as per product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Opdivo 120mg/12ml concentrate for solution for infusion vials (Bristol-Myers Squibb Pharmaceuticals Ltd)
Information as per product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Normal immunoglobulin human
Octagam 10% 10g/100ml solution for infusion bottles (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 252 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Octagam 10% 5g/50ml solution for infusion bottles (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 252 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Gammanorm 1.65g/10ml solution for injection vials (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Octagam 10% 2g/20ml solution for infusion vials (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 252 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Octagam 10% 20g/200ml solution for infusion bottles (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 252 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Octagam 5% 10g/200ml solution for infusion bottles (Octapharma Ltd)
Information outside product licence
| Maximum Time For excursion | 252 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Octagam 5% 5g/100ml solution for infusion bottles (Octapharma Ltd)
Information outside product licence
| Maximum Time For excursion | 252 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Gamunex 10% 5g/50ml solution for infusion vials (Grifols UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Gamunex 10% 10g/100ml solution for infusion vials (Grifols UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Gamunex 10% 20g/200ml solution for infusion vials (Grifols UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Gammanorm 2g/12ml solution for injection vials (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Gammanorm 4g/24ml solution for injection vials (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Gammanorm 8g/48ml solution for injection vials (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Gammanorm 1g/6ml solution for injection vials (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Cutaquig 1g/6ml solution for injection vials (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 252 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Cutaquig 2g/12ml solution for injection vials (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 252 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Cutaquig 4g/24ml solution for injection vials (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 252 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Cutaquig 8g/48ml solution for injection vials (Octapharma Ltd)
Information as per product licence
| Maximum Time For excursion | 252 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Nusinersen
Spinraza 12mg/5ml solution for injection vials (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Stability Data and Comments
Prior to administration, unopened vials of Spinraza can be removed from and returned to the refrigerator if necessary. If removed from the original carton, the total combined time out of refrigeration should not exceed 30 hours, at a temperature that does not exceed 25°C.
Ocriplasmin
Jetrea 0.375mg/0.3ml solution for injection vials (Inceptua AB)
Information as per product licence
| Maximum Time For excursion | 8 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
The product should be stored frozen. Once defrosted, the product may be kept in the fridge (2°C to 8°C) for up to 1 week. The product must then be used or discarded.
Octocog alfa
Advate 1,000unit powder and solvent for solution for injection vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Advate 1,500unit powder and solvent for solution for infusion vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Advate 2,000unit powder and solvent for solution for injection vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Advate 3,000unit powder and solvent for solution for infusion vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Advate 250unit powder and 2ml solvent for solution for injection vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Advate 250unit powder and 5ml solvent for solution for injection vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Advate 500unit powder and 2ml solvent for solution for injection vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Advate 500unit powder and 5ml solvent for solution for injection vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Octreotide
Sandostatin 100micrograms/1ml solution for injection ampoules (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Sandostatin 50micrograms/1ml solution for injection ampoules (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Sandostatin 500micrograms/1ml solution for injection ampoules (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Octreotide 50micrograms/1ml solution for injection ampoules (Sun Pharma UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Octreotide 100micrograms/1ml solution for injection ampoules (Sun Pharmaceutical Industries Europe B.V.)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Octreotide 500micrograms/1ml solution for injection ampoules (Sun Pharma UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Octreotide 1mg/5ml solution for injection vials (Sun Pharmaceutical Industries Europe B.V.)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Ofatumumab
Kesimpta Sensoready 20mg/0.4ml solution for injection pre-filled pens (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Stability Data and Comments
The product may be used within 14 days after a temperature excursion, provided it is returned to the fridge within 7 days.
Omalizumab
Xolair 75mg/0.5ml solution for injection pre-filled syringes (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Xolair 150mg/1ml solution for injection pre-filled syringes (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Oxytocin
Syntocinon 5units/1ml solution for injection ampoules (Exeltis UK Ltd)
Information outside product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Source for off-label information
Manufacturer data
Syntocinon 10units/1ml solution for injection ampoules (Exeltis UK Ltd)
Information outside product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Source for off-label information
Manufacturer data
Oxytocin 10units/1ml solution for infusion ampoules (Esteve Pharmaceuticals Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Oxytocin 5units/1ml solution for injection ampoules (Kent Pharma (UK) Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Oxytocin 10units/1ml solution for injection ampoules (Kent Pharma (UK) Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Palivizumab
Synagis 50mg/0.5ml solution for injection vials (AstraZeneca UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 40°C, the maximum time for excursion is reduced to 8 hours.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Synagis 100mg/1ml solution for injection vials (AstraZeneca UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 40°C, the maximum time for excursion is reduced to 8 hours.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Pancreatin
Pancrex V 125mg capsules (Essential Pharma Ltd)
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Pancrex V capsules (Essential Pharma Ltd)
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Pasireotide
Signifor 20mg powder and solvent for suspension for injection vials (Recordati Rare Diseases UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 6 Days |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Signifor 40mg powder and solvent for suspension for injection vials (Recordati Rare Diseases UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 6 Days |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Signifor 60mg powder and solvent for suspension for injection vials (Recordati Rare Diseases UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 6 Days |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | No |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Signifor 30mg powder and solvent for suspension for injection vials (Recordati Rare Diseases UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 6 Days |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Patiromer calcium
Veltassa 16.8g oral powder sachets (Vifor Fresenius Medical Care Renal Pharma UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Veltassa 8.4g oral powder sachets (Vifor Fresenius Medical Care Renal Pharma UK Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Pegfilgrastim
Neulasta 6mg/0.6ml solution for injection pre-filled syringes (Amgen Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Excursion Case
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 0 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Peginterferon beta-1a
Plegridy 63micrograms/0.5ml solution for injection pre-filled pens (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Plegridy 94micrograms/0.5ml solution for injection pre-filled pens (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Plegridy 63micrograms/0.5ml and 94micrograms/0.5ml solution for injection pre-filled pens treatment initiation pack (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Plegridy 125micrograms/0.5ml solution for injection pre-filled pens (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Plegridy 125micrograms/0.5ml solution for injection pre-filled syringes (Biogen Idec Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Pegvisomant
Somavert 10mg powder and solvent for solution for injection vials (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
The vial(s) must be protected from light
Somavert 15mg powder and solvent for solution for injection vials (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
The vial(s) must be protected from light
Somavert 20mg powder and solvent for solution for injection vials (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
The vial(s) must be protected from light
Somavert 25mg powder and solvent for solution for injection vials (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
The vial(s) must be protected from light
Somavert 30mg powder and solvent for solution for injection vials (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
The vial(s) must be protected from light
Pentostatin
Nipent 10mg powder for solution for injection vials (Pfizer Ltd)
Information outside product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Pneumococcal vaccine
Prevenar 13 vaccine suspension for injection 0.5ml pre-filled syringes (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 4 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -5 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Prevenar 20 vaccine suspension for injection 0.5ml pre-filled syringes (Pfizer Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 9 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
Manufacturer's website.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 9 Days |
|---|---|
| Temperature Range For excursion | -5 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
Manufacturer's website
Poractant alfa
Curosurf 240mg/3ml endotracheopulmonary suspension vials (Chiesi Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Curosurf 120mg/1.5ml endotracheopulmonary suspension vials (Chiesi Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Proxymetacaine
Minims proxymetacaine 0.5% eye drops 0.5ml unit dose (Bausch & Lomb UK Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Rabies vaccine
Rabipur vaccine powder and solvent for solution for injection 1ml pre-filled syringes (Bavarian Nordic UK Ltd)
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Ranibizumab
Lucentis 2.3mg/0.23ml solution for injection vials (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Lucentis 1.65mg/0.165ml solution for injection pre-filled syringes (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Ongavia 2.3mg/0.23ml solution for injection vials (Teva UK Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Risperidone
Risperdal Consta 37.5mg powder and solvent for prolonged-release suspension for injection vials (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Risperdal Consta 50mg powder and solvent for prolonged-release suspension for injection vials (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Risperdal Consta 25mg powder and solvent for prolonged-release suspension for injection vials (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Rituximab
Rixathon 100mg/10ml concentrate for solution for infusion vials (Sandoz Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Rixathon 500mg/50ml concentrate for solution for infusion vials (Sandoz Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Rocuronium
Esmeron 50mg/5ml solution for injection vials (Merck Sharp & Dohme (UK) Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Rocuronium bromide 50mg/5ml solution for injection ampoules (hameln pharma Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Rocuronium bromide 100mg/10ml solution for injection vials (Bowmed Ibisqus Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Rocuronium bromide 50mg/5ml solution for injection vials (Bowmed Ibisqus Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Rocuronium bromide 100mg/10ml solution for injection ampoules (Bowmed Ibisqus Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Rocuronium bromide 50mg/5ml solution for injection ampoules (Bowmed Ibisqus Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Rocuronium bromide 50mg/5ml solution for injection vials (AS Kalceks)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Ropeginterferon alfa-2b
Besremi 250micrograms/0.5ml solution for injection pre-filled pens (AOP Orphan Ltd)
Information outside product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Rurioctocog alfa pegol
Adynovi 2,000unit powder and solvent for solution for injection vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Adynovi 1,000unit powder and solvent for solution for injection vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Adynovi 250unit powder and solvent for solution for injection vials (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Sarilumab
Kevzara 150mg/1.14ml solution for injection pre-filled syringes (Sanofi Genzyme)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Kevzara 200mg/1.14ml solution for injection pre-filled syringes (Sanofi Genzyme)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Kevzara 150mg/1.14ml solution for injection pre-filled pens (Sanofi Genzyme)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Kevzara 200mg/1.14ml solution for injection pre-filled pens (Sanofi Genzyme)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Secukinumab
Cosentyx 150mg/1ml solution for injection pre-filled pens (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 4 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Cosentyx 150mg/1ml solution for injection pre-filled syringes (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 4 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Cosentyx 300mg/2ml solution for injection pre-filled pens (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 4 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Cosentyx 75mg/0.5ml solution for injection pre-filled syringes (Novartis Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 4 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Semaglutide
Ozempic 0.25mg/0.19ml solution for injection 1.5ml pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 42 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Ozempic 0.5mg/0.37ml solution for injection 1.5ml pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 42 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Ozempic 1mg/0.74ml solution for injection 3ml pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 42 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Setmelanotide
Imcivree 10mg/1ml solution for injection vials (Rhythm Pharmaceuticals UK Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Shingles (Herpes Zoster) vaccine
Shingrix (Herpes Zoster) adjuvanted recombinant vaccine powder and suspension for suspension for injection 0.5ml vials (GlaxoSmithKline UK Ltd)
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Siltuximab
Sylvant 400mg powder for concentrate for solution for infusion vials (Recordati UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 9 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 18 Days |
|---|---|
| Temperature Range For excursion | -18 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Sylvant 100mg powder for concentrate for solution for infusion vials (Recordati UK Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 9 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advice to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 18 Days |
|---|---|
| Temperature Range For excursion | -18 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Sirolimus
Rapamune 1mg/ml oral solution (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Somatrogon
Ngenla 24mg/1.2ml solution for injection pre-filled pens (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 4 hours |
|---|---|
| Temperature Range For excursion | 8°C to 32 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Stability Data and Comments
Up to 5 separate excursions of 4 hours each may occur.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Ngenla 60mg/1.2ml solution for injection pre-filled pens (Pfizer Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 4 hours |
|---|---|
| Temperature Range For excursion | 8°C to 32 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Stability Data and Comments
Up to 5 separate excursions of 4 hours each may occur.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Somatropin
Genotropin 12mg powder and solvent for solution for injection cartridges (Pfizer Ltd)
Information outside product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Genotropin 5.3mg powder and solvent for solution for injection cartridges (Pfizer Ltd)
Information outside product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Genotropin MiniQuick 200microgram powder and solvent for solution for injection pre-filled disposable devices (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Genotropin MiniQuick 400microgram powder and solvent for solution for injection pre-filled disposable devices (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Genotropin MiniQuick 600microgram powder and solvent for solution for injection pre-filled disposable devices (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Genotropin MiniQuick 800microgram powder and solvent for solution for injection pre-filled disposable devices (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Genotropin MiniQuick 1.2mg powder and solvent for solution for injection pre-filled disposable devices (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Genotropin MiniQuick 1mg powder and solvent for solution for injection pre-filled disposable devices (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Genotropin MiniQuick 1.4mg powder and solvent for solution for injection pre-filled disposable devices (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Genotropin MiniQuick 1.6mg powder and solvent for solution for injection pre-filled disposable devices (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Genotropin MiniQuick 1.8mg powder and solvent for solution for injection pre-filled disposable devices (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Genotropin MiniQuick 2mg powder and solvent for solution for injection pre-filled disposable devices (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Genotropin GoQuick 12mg powder and solvent for solution for injection pre-filled pens (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Genotropin GoQuick 5.3mg powder and solvent for solution for injection pre-filled pens (Pfizer Ltd)
Information as per product licence
| Maximum Time For excursion | 168 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Norditropin NordiFlex 15mg/1.5ml solution for injection pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Saizen 6mg/1.03ml solution for injection cartridges (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
After the first injection, when stored outside of the refrigerator for up to 7 days, the Saizen cartridge must be returned to the refrigerator and used within 28 days after first injection. For stability data regarding unopened injection cartridges, we recommend contacting the product's manufacturer directly.
Saizen 12mg/1.5ml solution for injection cartridges (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
After the first injection, when stored outside of the refrigerator for up to 7 days, the Saizen cartridge must be returned to the refrigerator and used within 28 days after first injection. For stability data regarding unopened injection cartridges, we recommend contacting the product's manufacturer directly.
Saizen 20mg/2.5ml solution for injection cartridges (Merck Serono Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
After the first injection, when stored outside of the refrigerator for up to 7 days, the Saizen cartridge must be returned to the refrigerator and used within 28 days after first injection. For stability data regarding unopened injection cartridges, we recommend contacting the product's manufacturer directly.
Norditropin NordiFlex 5mg/1.5ml solution for injection pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Norditropin NordiFlex 10mg/1.5ml solution for injection pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Norditropin FlexPro 15mg/1.5ml solution for injection pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Norditropin FlexPro 5mg/1.5ml solution for injection pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Norditropin FlexPro 10mg/1.5ml solution for injection pre-filled pens (Novo Nordisk Ltd)
Information as per product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Tafluprost
Saflutan 15micrograms/ml eye drops 0.3ml unit dose (Santen UK Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Saflutan 15micrograms/ml eye drops (Santen UK Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Tafluprost + Timolol
Taptiqom 15micrograms/ml / 5mg/ml eye drops 0.3ml unit dose (Santen UK Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Talimogene laherparepvec
Imlygic 100million plaque forming units/1ml solution for injection vials (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Stability Data and Comments
Imlygic must not be refrozen once it has thawed. Discard any thawed Imlygic in the vial or syringe stored longer than the specified times.
Imlygic 1million plaque forming units/1ml solution for injection vials (Amgen Ltd)
Information as per product licence
| Maximum Time For excursion | 12 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
Protect from light.
Stability Data and Comments
Imlygic must not be refrozen once it has thawed. Discard any thawed Imlygic in the vial or syringe stored longer than the specified times.
Tasonermin
Beromun 1mg powder for solution for infusion vials (Belpharma S.A)
Information as per product licence
| Maximum Time For excursion | 24 hours |
|---|---|
| Temperature Range For excursion | 8°C to 20 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Temsirolimus
Torisel 30mg/1.2ml concentrate for solution for infusion vials and diluent (Pfizer Ltd)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 21 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
| Additional actions following excursion | Yes |
If the excursion temperature exceeds 25°C but remains below 40°C, the maximum time for excursion is reduced to 5 days.
Stability Data and Comments
The diluent for temsirolimus concentrate for injection can withstand short-term temperature excursions of up to 5 days (120 hours) at 51°C; or up to 1 day (24 hours) at 70°C.
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Stability Data and Comments
The diluent for temsirolimus concentrate for injection can withstand short-term temperature excursions of up to 6 days (144 hours) at -20°C.
Source for off-label information
As advised to SPS by manufacturer.
Teriparatide
Sondelbay 20micrograms/80microlitres solution for injection 2.4ml pre-filled pens (Accord Healthcare Ltd)
Information as per product licence
| Maximum Time For excursion | 72 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Tetracaine
Ametop 4% gel (Alliance Pharmaceuticals Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Tildrakizumab
Ilumetri 100mg/1ml solution for injection pre-filled syringes (Almirall Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
| Additional actions following excursion | Yes |
This applies to a single period of exposure for unopened pre-filled syringes.
Tirzepatide
Mounjaro 2.5mg/0.5ml solution for injection pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mounjaro 5mg/0.5ml solution for injection pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mounjaro KwikPen 7.5mg/0.6ml solution for injection 2.4ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mounjaro KwikPen 15mg/0.6ml solution for injection 2.4ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mounjaro KwikPen 12.5mg/0.6ml solution for injection 2.4ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Mounjaro KwikPen 10mg/0.6ml solution for injection 2.4ml pre-filled pens (Eli Lilly and Company Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Tobramycin
Tobi 300mg/5ml nebuliser solution 5ml ampoules (Viatris UK Healthcare Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Bramitob 300mg/4ml nebuliser solution 4ml ampoules (Chiesi Ltd)
Information as per product licence
| Maximum Time For excursion | 84 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Vantobra 170mg/1.7ml nebuliser solution 1.7ml ampoules (Pari Medical Ltd)
Excursion Case
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Excursion Case
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Tocilizumab
RoActemra 162mg/0.9ml solution for injection pre-filled syringes (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
RoActemra 162mg/0.9ml solution for injection pre-filled pens (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Tyenne 80mg/4ml concentrate for solution for infusion vials (Fresenius Kabi Ltd)
Information as per product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within max time for excursion | Yes |
Tralokinumab
Adtralza 150mg/1ml solution for injection pre-filled syringes (LEO Pharma)
Information as per product licence
| Maximum Time For excursion | 14 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Trastuzumab
Herceptin 600mg/5ml solution for injection vials (Roche Products Ltd)
Information as per product licence
| Maximum Time For excursion | 6 hours |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Tremelimumab
Imjudo 300mg/15ml concentrate for solution for infusion vials (AstraZeneca UK Ltd)
Information outside product licence
| Maximum Time For excursion | 8 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
Provided by manufacturer to SPS
Tuberculosis vaccine
BCG Vaccine AJV powder for suspension for injection 1ml vials (AJ Vaccines)
Excursion Case
Information outside product licence
| Maximum Time For excursion | 12 hours |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Excursion Case
Information outside product licence
| Maximum Time For excursion | 5 Days |
|---|---|
| Temperature Range For excursion | -20 °C to 2°C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Ustekinumab
Stelara 45mg/0.5ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Stelara 90mg/1ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)
Information as per product licence
| Maximum Time For excursion | 30 Days |
|---|---|
| Temperature Range For excursion | 8°C to 30 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Vedolizumab
Entyvio 108mg/0.68ml solution for injection pre-filled syringes (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Entyvio 108mg/0.68ml solution for injection pre-filled pens (Takeda UK Ltd)
Information as per product licence
| Maximum Time For excursion | 7 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Vincristine
Vincristine 1mg/1ml solution for injection vials (Pfizer Ltd)
Information outside product licence
| Maximum Time For excursion | 28 Days |
|---|---|
| Temperature Range For excursion | 8°C to 25 °C |
| Return to the fridge | No |
| Use product within max time for excursion | Yes |
Source for off-label information
Provided by manufacturer
Vinorelbine
Navelbine 50mg/5ml concentrate for solution for infusion vials (Pierre Fabre Ltd)
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 32 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Navelbine 10mg/1ml concentrate for solution for infusion vials (Pierre Fabre Ltd)
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 32 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Navelbine 20mg capsules (Pierre Fabre Ltd)
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 32 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Navelbine 30mg capsules (Pierre Fabre Ltd)
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 32 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.
Navelbine 80mg capsules (Pierre Fabre Ltd)
Information outside product licence
| Maximum Time For excursion | 48 hours |
|---|---|
| Temperature Range For excursion | 8°C to 32 °C |
| Return to the fridge | Yes |
| Use product within original expiry date | Yes |
Source for off-label information
As advised to SPS by manufacturer.