Refrigerated medicines stability tool

Search for advice on whether refrigerated medicines can or can't be used after exposure to out-of-range temperatures.

Information from both product licences and other sources is being shown Information from product licences only is being shown

Adalimumab

Adalimumab
Humira 40mg/0.4ml solution for injection pre-filled pens (AbbVie Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Adalimumab
Humira 40mg/0.4ml solution for injection pre-filled syringes (AbbVie Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Adalimumab
Humira 20mg/0.2ml solution for injection pre-filled syringes (AbbVie Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Adalimumab
Amgevita 40mg/0.8ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Adalimumab
Amgevita 40mg/0.8ml solution for injection pre-filled pens (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Adalimumab
Hyrimoz 40mg/0.8ml solution for injection pre-filled pens (Sandoz Ltd)

Information as per product licence

  • Maximum Time For excursion

    21 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Adalimumab
Hyrimoz 40mg/0.8ml solution for injection pre-filled syringes (Sandoz Ltd)

Information as per product licence

  • Maximum Time For excursion

    21 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Adalimumab
Humira 80mg/0.8ml solution for injection pre-filled pens (AbbVie Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Adalimumab
Amgevita 20mg/0.4ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Adalimumab
Imraldi 40mg/0.8ml solution for injection pre-filled pens (Biogen Idec Ltd)

Information as per product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Adalimumab
Imraldi 40mg/0.8ml solution for injection pre-filled syringes (Biogen Idec Ltd)

Information as per product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Aflibercept

Aflibercept
Eylea 4mg/100microlitres solution for injection vials (Bayer Plc)

Information as per product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Aflibercept
Eylea 3.6mg/90microlitres solution for injection pre-filled syringes (Bayer Plc)

Information as per product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Alirocumab

Alirocumab
Praluent 75mg/1ml solution for injection pre-filled pens (Sanofi)

Information as per product licence

  • Maximum Time For excursion

    30 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Alirocumab
Praluent 150mg/1ml solution for injection pre-filled pens (Sanofi)

Information as per product licence

  • Maximum Time For excursion

    30 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Alirocumab
Praluent 300mg/2ml solution for injection pre-filled pens (Sanofi)

Information as per product licence

  • Maximum Time For excursion

    30 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Alprostadil

Alprostadil
Muse 500microgram urethral sticks (Viatris UK Healthcare Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Alprostadil
Muse 1000microgram urethral sticks (Viatris UK Healthcare Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Alprostadil
Caverject 40microgram powder and solvent for solution for injection vials (Pfizer Ltd)

Information outside product licence

  • Maximum Time For excursion

    4 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Alprostadil
Vitaros 3mg/g cream (The Simple Pharma Company UK Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Amikacin liposomal

Amikacin liposomal
Arikayce liposomal 590mg nebuliser dispersion vials with Lamira Nebuliser Handset (Insmed Ltd)

Information as per product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Anakinra

Anakinra
Kineret 100mg/0.67ml solution for injection pre-filled syringes (Swedish Orphan Biovitrum Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Angiotensin II

Angiotensin II
Giapreza 2.5mg/1ml concentrate for solution for infusion vials (PAION Netherlands B.V.)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    48 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    6 Days
  • Temperature Range For excursion

    -20 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Anidulafungin

Anidulafungin
Ecalta 100mg powder for concentrate for solution for infusion vials (Pfizer Ltd)

Information as per product licence

  • Maximum Time For excursion

    4 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Anti-D immunoglobulin

Anti-D immunoglobulin
D-Gam Anti-D immunoglobulin 500unit solution for injection vials (Bio Products Laboratory Ltd)
Excursion Case

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    0 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Antithymocyte immunoglobulin (rabbit)

Antithymocyte immunoglobulin (rabbit)
Thymoglobuline 25mg powder and solvent for solution for infusion vials (Sanofi)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Argipressin

Argipressin
Argipressin 20units/1ml solution for injection ampoules (AOP Orphan Ltd)

Information outside product licence

  • Maximum Time For excursion

    84 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Asfotase alfa

Asfotase alfa
Strensiq 40mg/1ml solution for injection vials (Alexion Pharma UK Ltd)

Information as per product licence

  • Maximum Time For excursion

    3 hours
  • Temperature Range For excursion

    8°C to 27 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Asfotase alfa
Strensiq 80mg/0.8ml solution for injection vials (Alexion Pharma UK Ltd)

Information as per product licence

  • Maximum Time For excursion

    3 hours
  • Temperature Range For excursion

    8°C to 27 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Asparaginase

Asparaginase
Spectrila 10,000unit powder for concentrate for solution for infusion vials (medac UK)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS from manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    48 hours
  • Temperature Range For excursion

    -1 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS from manufacturer.

Atracurium

Atracurium
Atracurium besilate 50mg/5ml solution for injection ampoules (Pfizer Ltd)

Information outside product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Atracurium
Atracurium besilate 25mg/2.5ml solution for injection ampoules (Pfizer Ltd)

Information outside product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Atracurium
Atracurium besilate 250mg/25ml solution for injection vials (Pfizer Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    -20 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Atracurium
Atracurium besilate 25mg/2.5ml solution for injection ampoules (Consilient Health Ltd)

Information outside product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Source for off-label information

As advised by SPS Quality Assurance.

Atracurium
Atracurium besilate 50mg/5ml solution for injection ampoules (Consilient Health Ltd)

Information outside product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Source for off-label information

As advised by SPS QA.

Atracurium
Atracurium besilate 25mg/2.5ml solution for injection ampoules (AS Kalceks)

Information outside product licence

  • Maximum Time For excursion

    48 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Atracurium
Atracurium besilate 50mg/5ml solution for injection ampoules (AS Kalceks)

Information outside product licence

  • Maximum Time For excursion

    48 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Aztreonam

Aztreonam
Cayston 75mg powder and solvent for nebuliser solution vials with Altera Nebuliser Handset (Gilead Sciences Ltd)
Excursion Case

Information as per product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    730 Days
  • Temperature Range For excursion

    -20 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Beclometasone + Formoterol

Beclometasone + Formoterol
Fostair 100micrograms/dose / 6micrograms/dose inhaler (Chiesi Ltd)

Information as per product licence

  • Maximum Time For excursion

    84 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Beclometasone + Formoterol
Fostair 200micrograms/dose / 6micrograms/dose inhaler (Chiesi Ltd)

Information as per product licence

  • Maximum Time For excursion

    84 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Beclometasone + Formoterol
Luforbec 100micrograms/dose / 6micrograms/dose inhaler (Lupin Healthcare (UK) Ltd)

Information as per product licence

  • Maximum Time For excursion

    84 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Beclometasone + Formoterol
Luforbec 200micrograms/dose / 6micrograms/dose inhaler (Lupin Healthcare (UK) Ltd)

Information as per product licence

  • Maximum Time For excursion

    84 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Beclometasone + Formoterol + Glycopyrronium bromide

Beclometasone + Formoterol + Glycopyrronium bromide
Trimbow 87micrograms/dose / 5micrograms/dose / 9micrograms/dose inhaler (Chiesi Ltd)
Excursion Case

Information as per product licence

  • Maximum Time For excursion

    56 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

This information applies only to the 60 actuation pressurised container.

Excursion Case

Information as per product licence

  • Maximum Time For excursion

    112 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

This information applies only to the 120 actuation pressurised container.

Beclometasone + Formoterol + Glycopyrronium bromide
Trimbow 172micrograms/dose / 5micrograms/dose / 9micrograms/dose inhaler (Chiesi Ltd)
Excursion Case

Information as per product licence

  • Maximum Time For excursion

    56 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

This information applies only to the 60 actuation pressurised container.

Excursion Case

Information as per product licence

  • Maximum Time For excursion

    84 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

This information applies only to the 120 actuation pressurised container.

Belantamab mafodotin

Belantamab mafodotin
Blenrep 100mg powder for concentrate for solution for infusion vials (GlaxoSmithKline UK Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    5 Days
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

If the excursion temperature exceeds 30°C but remains below 40°C, the maximum time for excursion is reduced to 24 hours.

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    5 Days
  • Temperature Range For excursion

    -20 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Belimumab

Belimumab
Benlysta 400mg powder for concentrate for solution for infusion vials (GlaxoSmithKline UK Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    21 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light. If product exposed to light, maximum time for excursion is reduced to 72 hours.

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    -25 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Belimumab
Benlysta 120mg powder for concentrate for solution for infusion vials (GlaxoSmithKline UK Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    21 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light. If product exposed to light, maximum time for excursion is reduced to 72 hours.

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    -25 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Belimumab
Benlysta 200mg/1ml solution for injection pre-filled pens (GlaxoSmithKline UK Ltd)

Information as per product licence

  • Maximum Time For excursion

    12 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Benralizumab

Benralizumab
Fasenra 30mg/1ml solution for injection pre-filled syringes (AstraZeneca UK Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Benralizumab
Fasenra 30mg/1ml solution for injection pre-filled pens (AstraZeneca UK Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Benzoyl peroxide + Clindamycin

Benzoyl peroxide + Clindamycin
Duac Once Daily gel (3% and 1%) (Stiefel Laboratories (UK) Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    48 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

If the excursion temperature exceeds 25°C but remains below 40°C, the maximum time for excursion is reduced to 4 hours.

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    6 Days
  • Temperature Range For excursion

    -1 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Benzoyl peroxide + Clindamycin
Duac Once Daily gel (5% and 1%) (Stiefel Laboratories (UK) Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    48 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

If the excursion temperature exceeds 25°C but remains below 40°C, the maximum time for excursion is reduced to 4 hours.

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    6 Days
  • Temperature Range For excursion

    -1 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Beractant

Beractant
Survanta 200mg/8ml endotracheopulmonary suspension bottles (AbbVie Ltd)

Information outside product licence

  • Maximum Time For excursion

    8 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Bimekizumab

Bimekizumab
Bimzelx 160mg/1ml solution for injection pre-filled syringes (UCB Pharma Ltd)

Information as per product licence

  • Maximum Time For excursion

    25 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Bimekizumab
Bimzelx 160mg/1ml solution for injection pre-filled pens (UCB Pharma Ltd)

Information as per product licence

  • Maximum Time For excursion

    25 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Brodalumab

Brodalumab
Kyntheum 210mg/1.5ml solution for injection pre-filled syringes (LEO Pharma)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Brolucizumab

Brolucizumab
Beovu 19.8mg/0.165ml solution for injection pre-filled syringes (Novartis Pharmaceuticals UK Ltd)

Information as per product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Bulevirtide

Bulevirtide
Hepcludex 2mg powder for solution for injection vials (Gilead Sciences Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    168 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    use product expiry date
  • Temperature Range For excursion

    -20 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Burosumab

Burosumab
Crysvita 10mg/1ml solution for injection vials (Kyowa Kirin Ltd)

Information outside product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Burosumab
Crysvita 20mg/1ml solution for injection vials (Kyowa Kirin Ltd)

Information outside product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Burosumab
Crysvita 30mg/1ml solution for injection vials (Kyowa Kirin Ltd)

Information outside product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Caplacizumab

Caplacizumab
Cablivi 10mg powder and solvent for solution for injection vials (Sanofi Genzyme)

Information as per product licence

  • Maximum Time For excursion

    56 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Carboprost

Carboprost
Hemabate 250micrograms/1ml solution for injection ampoules (Pfizer Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    15 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

If the excursion temperature exceeds 25°C but remains below 40°C, the maximum time for excursion is reduced to 48 hours.

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    48 hours
  • Temperature Range For excursion

    -20 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Carglumic acid

Carglumic acid
Carbaglu 200mg dispersible tablets (Recordati Rare Diseases UK Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 15 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

If the excursion temperature exceeds 15°C but remains below 25°C, the maximum time for excursion is reduced to 72 hours.

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    -20 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Cefiderocol

Cefiderocol
Fetcroja 1g powder for concentrate for solution for infusion vials (Shionogi BV)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    6 hours
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    6 hours
  • Temperature Range For excursion

    -20 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Certolizumab pegol

Certolizumab pegol
Cimzia 200mg/1ml solution for injection pre-filled syringes (UCB Pharma Ltd)
Excursion Case

Information as per product licence

  • Maximum Time For excursion

    10 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Discard product if exposed to greater than one excursion.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    10 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Discard product if exposed to greater than one excursion.

Source for off-label information

As advised to SPS by manufacturer.

Certolizumab pegol
Cimzia 200mg/1ml solution for injection pre-filled pens (UCB Pharma Ltd)
Excursion Case

Information as per product licence

  • Maximum Time For excursion

    10 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Discard product if exposed to greater than one excursion.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    10 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Discard product if exposed to greater than one excursion.

Source for off-label information

As advised to SPS by manufacturer.

Certolizumab pegol
Cimzia 200mg/1ml solution for injection in a dose-dispenser cartridge (UCB Pharma Ltd)
Excursion Case

Information as per product licence

  • Maximum Time For excursion

    10 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Discard product if exposed to greater than one excursion.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    10 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Discard product if exposed to greater than one excursion.

Source for off-label information

As advised to SPS by manufacturer.

Chloramphenicol

Chloramphenicol
Minims chloramphenicol 0.5% eye drops 0.5ml unit dose (Bausch & Lomb UK Ltd)

Information as per product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Chlormethine

Chlormethine
Ledaga 160micrograms/g gel (Recordati Rare Diseases UK Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    12 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    -15 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Cholera vaccine

Cholera vaccine
Dukoral cholera vaccine effervescent powder and suspension for oral suspension (Valneva UK Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Choriogonadotropin alfa

Choriogonadotropin alfa
Ovitrelle 250micrograms/0.5ml solution for injection pre-filled syringes (Merck Serono Ltd)

Information as per product licence

  • Maximum Time For excursion

    30 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Cisatracurium

Cisatracurium
Cisatracurium besilate 150mg/30ml solution for injection vials (Accord-UK Ltd)

Information outside product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Source for off-label information

As advised by SPS Quality Assurance.

Cisatracurium
Cisatracurium besilate 20mg/10ml solution for injection ampoules (Consilient Health Ltd)

Information outside product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Source for off-label information

As advised by SPS Quality Assurance.

Cladribine

Cladribine
Litak 10mg/5ml solution for injection vials (Lipomed GmbH)

Information outside product licence

  • Maximum Time For excursion

    730 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

If the excursion temperature exceeds 25°C but remains below 30°C, the maximum time for excursion is reduced to 1 year.

Source for off-label information

As advised to SPS by manufacturer.

Crisantaspase

Crisantaspase
Erwinase 10,000unit powder for solution for injection vials (Porton Biopharma Ltd)

Information outside product licence

  • Maximum Time For excursion

    28 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Daratumumab

Daratumumab
Darzalex 1800mg/15ml solution for injection vials (Janssen-Cilag Ltd)

Information as per product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa

Darbepoetin alfa
Aranesp 20micrograms/0.5ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp 30micrograms/0.3ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp 40micrograms/0.4ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp 50micrograms/0.5ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp 60micrograms/0.3ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp 10micrograms/0.4ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp 80micrograms/0.4ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp 100micrograms/0.5ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp 150micrograms/0.3ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp 500micrograms/1ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp 300micrograms/0.6ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp SureClick 500micrograms/1ml solution for injection pre-filled pens (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp SureClick 20micrograms/0.5ml solution for injection pre-filled pens (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp SureClick 40micrograms/0.4ml solution for injection pre-filled pens (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp SureClick 60micrograms/0.3ml solution for injection pre-filled pens (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp SureClick 80micrograms/0.4ml solution for injection pre-filled pens (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp SureClick 100micrograms/0.5ml solution for injection pre-filled pens (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp SureClick 150micrograms/0.3ml solution for injection pre-filled pens (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp SureClick 300micrograms/0.6ml solution for injection pre-filled pens (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Darbepoetin alfa
Aranesp 130micrograms/0.65ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Denosumab

Denosumab
Prolia 60mg/1ml solution for injection pre-filled syringes (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    30 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Denosumab
Xgeva 120mg/1.7ml solution for injection vials (Amgen Ltd)

Information as per product licence

  • Maximum Time For excursion

    30 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

Protect from light.

Digoxin specific antibody

Digoxin specific antibody
DigiFab 40mg powder for solution for infusion vials (Protherics Medicines Development Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    -20 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Diphtheria + Tetanus + Pertussis + Hepatitis B + Poliomyelitis + Haemophilus influenzae type B vaccine

Diphtheria + Tetanus + Pertussis + Hepatitis B + Poliomyelitis + Haemophilus influenzae type B vaccine
Infanrix Hexa vaccine powder and suspension for suspension for injection 0.5ml pre-filled syringes (GlaxoSmithKline UK Ltd)
Excursion Case

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    use product expiry date
  • Temperature Range For excursion

    0 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Diphtheria + Tetanus + Pertussis + Hepatitis B + Poliomyelitis + Haemophilus influenzae type B vaccine
Vaxelis vaccine suspension for injection 0.5ml pre-filled syringes (Sanofi)

Information as per product licence

  • Maximum Time For excursion

    9 Days 12 Hrs
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Diphtheria + Tetanus + Pertussis + Poliomyelitis + Haemophilus influenzae type B vaccine

Diphtheria + Tetanus + Pertussis + Poliomyelitis + Haemophilus influenzae type B vaccine
Infanrix-IPV + Hib vaccine powder and suspension for suspension for injection 0.5ml pre-filled syringes (GlaxoSmithKline UK Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    use product expiry date
  • Temperature Range For excursion

    0 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Diphtheria + Tetanus + Pertussis + Poliomyelitis vaccine

Diphtheria + Tetanus + Pertussis + Poliomyelitis vaccine
Boostrix-IPV suspension for injection 0.5ml pre-filled syringes (GlaxoSmithKline UK Ltd)

Information as per product licence

  • Maximum Time For excursion

    8 hours
  • Temperature Range For excursion

    8°C to 21 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Dornase alfa

Dornase alfa
Pulmozyme 2.5mg nebuliser liquid 2.5ml ampoules (Roche Products Ltd)

Information as per product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Dostarlimab

Dostarlimab
Jemperli 500mg/10ml concentrate for solution for infusion vials (GlaxoSmithKline UK Ltd)

Information outside product licence

  • Maximum Time For excursion

    40 hours
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Doxorubicin

Doxorubicin
Doxorubicin 50mg/25ml solution for infusion vials (medac UK)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    12 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

If excursion time exceeds 12 hours, use product within 14 days.

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    use product expiry date
  • Temperature Range For excursion

    0 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Doxorubicin
Doxorubicin 200mg/100ml solution for infusion vials (medac UK)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    12 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

If excursion time exceeds 12 hours, use product within 14 days.

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    use product expiry date
  • Temperature Range For excursion

    0 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Doxorubicin
Doxorubicin 10mg/5ml solution for infusion vials (medac UK)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    12 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes
  • Additional actions following excursion

    Yes
Additional actions following excursion

If excursion time exceeds 12 hours, use product within 14 days.

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    use product expiry date
  • Temperature Range For excursion

    0 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Doxycycline

Doxycycline
Doxycyclin-ratiopharm SF 100mg/5ml solution for injection ampoules (Imported (Germany))

Information outside product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Dulaglutide

Dulaglutide
Trulicity 0.75mg/0.5ml solution for injection pre-filled pens (Eli Lilly and Company Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Dulaglutide
Trulicity 1.5mg/0.5ml solution for injection pre-filled pens (Eli Lilly and Company Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Dulaglutide
Trulicity 3mg/0.5ml solution for injection pre-filled pens (Eli Lilly and Company Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Dulaglutide
Trulicity 4.5mg/0.5ml solution for injection pre-filled pens (Eli Lilly and Company Ltd)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Dupilumab

Dupilumab
Dupixent 300mg/2ml solution for injection pre-filled syringes (Sanofi Genzyme)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Dupilumab
Dupixent 200mg/1.14ml solution for injection pre-filled syringes (Sanofi Genzyme)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Dupilumab
Dupixent 200mg/1.14ml solution for injection pre-filled pens (Sanofi Genzyme)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Dupilumab
Dupixent 300mg/2ml solution for injection pre-filled pens (Sanofi Genzyme)

Information as per product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within max time for excursion

    Yes

Durvalumab

Durvalumab
Imfinzi 500mg/10ml concentrate for solution for infusion vials (AstraZeneca UK Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    8°C to 40 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    0 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Durvalumab
Imfinzi 120mg/2.4ml concentrate for solution for infusion vials (AstraZeneca UK Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    8°C to 40 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    24 hours
  • Temperature Range For excursion

    0 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Eculizumab

Eculizumab
Soliris 300mg/30ml concentrate for solution for infusion vials (Alexion Pharma UK Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Emicizumab

Emicizumab
Hemlibra 30mg/1ml solution for injection vials (Roche Products Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Emicizumab
Hemlibra 60mg/0.4ml solution for injection vials (Roche Products Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Emicizumab
Hemlibra 105mg/0.7ml solution for injection vials (Roche Products Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Emicizumab
Hemlibra 150mg/1ml solution for injection vials (Roche Products Ltd)

Information as per product licence

  • Maximum Time For excursion

    7 Days
  • Temperature Range For excursion

    8°C to 30 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Enfortumab vedotin

Enfortumab vedotin
Padcev 30mg powder for concentrate for solution for infusion vials (Astellas Pharma Ltd)
Excursion Case

Information outside product licence

  • Maximum Time For excursion

    168 Days
  • Temperature Range For excursion

    8°C to 40 °C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Excursion Case

Information outside product licence

  • Maximum Time For excursion

    14 Days
  • Temperature Range For excursion

    -80 °C to 2°C
  • Return to the fridge

    Yes
  • Use product within original expiry date

    Yes

Source for off-label information

As advised to SPS by manufacturer.

Epoetin alfa

Epoetin alfa
Eprex 4,000units/0.4ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Epoetin alfa
Eprex 2,000units/0.5ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Epoetin alfa
Eprex 1,000units/0.5ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Epoetin alfa
Eprex 3,000units/0.3ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Epoetin alfa
Eprex 5,000units/0.5ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Epoetin alfa
Eprex 6,000units/0.6ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Epoetin alfa
Eprex 8,000units/0.8ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Epoetin alfa
Eprex 10,000units/1ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge

    No
  • Use product within max time for excursion

    Yes

Epoetin alfa
Eprex 20,000units/0.5ml solution for injection pre-filled syringes (Janssen-Cilag Ltd)

Information as per product licence

  • Maximum Time For excursion

    72 hours
  • Temperature Range For excursion

    8°C to 25 °C
  • Return to the fridge